[Brian Pfleuger]

For 270WSM with 150gr Nosler BT, QuickLoad thinks your best powder without going heavily compressed would be:

Ramshot Magnum
VVH N560
Accurate MagPro
IMR 7828 (and/or ssc)
RL-22

There is only about 30fps difference between them.

For .25-06 with 120gr Sierra, it thinks:

VVH N560
Ramshot Magnum
IMR 7828 (and/or ssc)
Accurate MagPro
RL-22

There is only about 35fps difference between them.

Velocity in the .25-06 with that bullet in a 26" barrel is expected to be 3,275-ish.

Retumbo loads would be 108% compressed and 150fps slower.