99.9% of the time, the appropriate response is to draw your weapon and say "STOP OR I'LL SHOOT", or some variation thereof, which will cause the potential BG to stop--- lest he be shot.
99% of the .1% of the time, one or two shots will be entirely sufficient, from any gun in any caliber.
I have better things to do than worry about the remaining 1% of the .1%.
One of those better things to do is talk to people on the internet who DO worry about the 1% of .1%.