Stability would be the only issue. I've seen but not tried any of the various 160 grain offerings I've seen here and there. The 150 grain BTSP's I've tried never seemed to group as well as the 150 RN's though the 130 SST's and 100 SP's I shoot group better. This in my M77 w/ 1:10" twist. The 270 Win rifles w/ 1:9 and 1:9.5 would probably like 160's
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