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most people stay away from the heavier loads in the .45 colt /bp conversions. They are really intended for the cowboy loads that tend to put the 250 grain bullets out in the mid 700fps range. These loads are not a bad choice for home defense and it is debatable if any of the more recent testosterone loads are really any more effective.
You would definately want to avoid the Buffalo Bore or Corbon hunting loads as these are intended for the full sized ruger blackhawks, redhawks freedom arms and such like. They carry warnings against their use in single action armies or the replicas
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