Have shot quite a few deer with both calibers. I started out with the 243 and moved to the 06 because of my own poor bullet selection. I kept trying to shoot various 80 grainers with poor results. I couldn't find one that would hold together. By the time I figured out that I better stick with the 100's I had already moved to the 06.
All my kids have started out on the 243 with 100's and then moved to whatever gun that tickled them.
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