Have you considered a .44magnum just in case you don't want to reload almost all your non-practice ammo?
Most commercial .45LC except for Buffalo Bore (who make great stuff) and few others are "cowboy loads." The .454Casull is a not easy to find commercially most of the time.
Between the two I would go with the Blackhawk because I find the any nose Alaskan in .454 a bit too stout in recoil for my taste. (I chose a Redhawk 5.5" in .44mag about 2 years ago to fill the niche you described. I am very happy with the choice.)
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