.22-250s generally shoot really well, but most of them are not purpose built match guns, they are varmint guns, where the difference of 1/4" in group size isn't a huge concern.
My first one was in the early 70s and was made on a Mauser action by our local gunsmith. Mauser 98 action, Douglas 26" tube (medium contour not a bull or a feastherweight barrel), Bishop stock and topped with an old Weaver K8 with fine crosswires. And that's where the smith stopped. I added a scope safety and a Timney target trigger.
Shooing off a rolled up field jacket, on the hood of a pickup, using Rem factory 55gr SPs that gun would put 3 in a group you could cover with a dime at 100yds.
EVERY SINGLE TIME....if the shooter did their part right.
This was outstanding for crows and woodchucks to 300yds, a bit more when the stars lined up just right. Other cartridges always ruled the "all bullets in one hole" game, where the .22-250 shined was hunting accuracy and high speed.
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All else being equal (and it almost never is) bigger bullets tend to work better.
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