My 2ยข is to just get a 12 gauge pump and feet it some 00.
I'm sure the guvn'r can be plenty lethal though. Hickok45 does a decent comparison of most ammo types that go thru a Judge. That should give you an idea if you think it's appropriate for your home.
http://m.youtube.com/watch?v=qRlry5KH6I0