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If efficiency is a priority, .357 on all accounts.
If fun factor is included, big .45's are the epitome of FUN.
44-40 is a fine, harder to load, more expensive cartridge that is very nostalgic, and accurate.
YMMV,
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Yes, in fact I do have a 454... in more ways than one. 
"No provision in our Constitution ought to be dearer to man than that which protects the rights of conscience against the enterprises of the civil authority" - Thomas Jefferson
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