For my part, I'll just say that I can comfortably shoot several hundred rounds of .45 ACP in an afternoon through an M&P with a smile on my face, but a few cylinders of .357, even through a full size GP-100, is enough to make me call it a day. Whether measuring in recoil or muzzle blast, for me the .45 is FAR more pleasant to shoot, even in +P loadings. YMMV.
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