I think you will be happier using .44 Magnum data, as long as you stick with powders that burn faster than H-110 or 296. (AA#7, AA#9, 2400, 4100, and Blue Dot should all be good choices.)
About 12.5 grains of Herco with a 250 or 255 grain cast bullet should give you an honest 1300 fps.
Ballistically, there's not a lot of difference between a SR primer and a LP primer. Don't worry about that.
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Do any of you use .452 sized bullets or mainly just stick with .454 in hardcast.
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I think you want to stick with .452 in cast bullets, not .454, and 451 should be fine for jacketed bullets.