Buckshot, of any size or gauge, is unreliable. Moreso past 30 to 40 yards.
Use a slug(Hornady makes a 250 grain, SST, 20 gauge) and rifle sights or a low magnification scope. A lot depends on what shotgun you have. No hunting with ammo you haven't sighted in with though.
There are "Ruger only" loads on Hodgdon's site. No mention of New or Old. Hodgdon's MBA's are just as frightened of law suits as Ruger's MBA's.
However, since you're not reloading, you need try a box of as many brands as you can to find the ammo your Vaquero shoots best. If it doesn't have adjustable sights, I'd suggest you refrain from hunting with it.
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