Random thoughts...
As you note, Dave, the .410 is a limited range tool.
But, in most folks' homes, we are talking about limited ranges.
Within its limited range, a .410 ought to be a more potent and more easily aimed defensive tool than a handgun, and if the recoil is more tolerable and encourages more practice, it's probably a net gain.
Since there's an exception to every rule, though, I guess I'll also observe that although I far prefer a shoulder weapon for defensive use in most situations, if you are having to move around a house with a gun (a situation we will hope never happens), in many houses a handgun just might be superior even though it is harder to aim and delivers a less potent defensive force -- because the shoulderarm is harder to maneuver and (especially for those not well trained) the take-away potential of a long arm is probably greater.
Gotta estimate your own circumstances and do the best you can to anticiapte how problems may arise and develop!
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