I use a Barnes 100 gr in 25-06. I believe that a 25 caliber is slightly small for the game cartridge. I do hunt rather large bodied whitetails with it. I believe that a 243 is also on the small side for deer. I would use it with out any reservations, provided you use a premium bullet. It is very hard for anyone to say that a Nosler Partition is an inferior bullet. You do need to check the accuracy of that load in her rifle. If it is not acceptable try another load.
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