I load a 44 Mag case with 225 grain gas check RCBS cast bullet over 7.0 grains of Titegroup. I've shot about 500 of them out of various 44 Mag guns with no problem. One of my favorite target loads is a 205 grain cast wadcutter from a Lee bullet mold over 5.9 grains of Titegoup with a velocity from my Dan Wesson 44 Mag at 917 fps. I have shoot about 1K of this load in the last year.