Surprising that universal clays has not been mentioned yet. For low to mid range loads, it can't be beat IMHO.
I first read about this powder many years ago (when gun mags actually did pieces on powders). It got very high marks from the writer, so I went and got some. It has been one of my favorite powders ever since. Economical, decent power and accuracy, and CLEAN.
While it is absolutely true that no single powder does it all (even within the range of a single caliber in some cases), universal is my main go-to powder for .38/.357, .40, and .44 Lite magnums.