FWIW... I've been loading for a long time, and have loaded many thousands of handgun rounds on my 550 (started life as a 450). Outside of 4-5 handgun rounds, I also load for: .221RFB, .222 Rem, .308 Win, .220 Imp, .338 WMag, 6MM Imp, .30-30 - all on my single stage presses. I'm a varmint hunter, and need my loads to be precise. In the rifle, that means single-stage. By all means get the 650, its a great machine, but get a single stage press for the rifles if you want their full potential. My opinion - worth what ya paid for it...
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Shoot carefully... swifter...