I shot the same load in a custom 270WSM using Fed 215M and Fed 215 and running those loads over a 35 Oehler Chronograph I got 2fps difference. I load at the range and I change primers working up loads. All my loads are for hunting or varmint rifles.
As the the OP question I use a hand priming tool and each priming tool I have is set up for case head/primer size so the one I use for 22-250/30-06 etc never get change. My primers go in square some on new cases may be little tight is all.
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