I really don't notice much difference between slugs, buck shot, and bird shot out of my 12ga. And I shoot shotguns alot!
WIth that said; IF you can shoot hogs with a .22 centerfire.... .223 or 22-250 will work if you stay at or under 200# hogs. I've shot a lot of hogs with my AR-15. I wouldn't try a bigger one than that though.
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