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It was/ is John Farnam that advocates "stitching them up the middle", going for the Aorta and up into the Thoracic triangle.
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From what I understand, the 10-round zipper stitch with .22 LR, starting at the crotch and finishing at the forehead, was the preferred tactic used very effectively in Chicago drug gang wars during the '70s. The near absence of recoil helps, but more so is the fact that these were assassinations, not self-defense encounters. The assassins got close by stealth or by deceipt, and they were acting, not reacting.