There are several schools that offer an integrated curriculum for defensive skills.
WWW.optionsforpersonalsecurity.com
WWW.insightstraining.com
These are two that I have trained with and respect a great deal.
WWW.tdiohio
This is a third that I have heard very good thing about but have not trained at.
OPS and Insights both offer mobil training throughout the country.
All three schools integrate their unarmed programs with teir knife programs with their pistol, shotgun and rifle training.
You can get a much broader training experience for a lot less money working with mobil training schools than having to make the trek to one of the big temples [Gunsite, Thunder Ranch, etc.]