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The biggest one is that Ruger is six rounds while Taurus Raging Bull is 5 rounds in 454.
Then Taurus is ported which does helps with muzzle flip a lot, but since you talk about Alaskan I assume you compare it to 2.5" barreled Raging Bull - that port takes about 0.75" of bore out of that 2.5" barrel leaving it essentially 1.75" barrel.
Another quite significant difference is that you'll need both hands to unlock cylinder on Taurus - it has two independent latches, one in normal location and one in front of cylinder, kind of like Dan Wesson.
And while Raging Bull line have pretty good reviews (unlike some other Taurus made guns), Ruger is much more robust gun.
And those Taurus grips are probably one of the best grips (in terms of dealing with recoil) I have shot
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