Out of the 243 and 308 I would be leaning towards the 243. The 243 with heiver bullets 90+gr will buck the wind rather well ofcourse not to the degree of the 308 but shoot 300 yards is a long shot on a yote. Plus you can get them 58gr V-max bullets that will stright up blow a stinking hole in a yote plus you can get them moving rather quick.
I would go for a savage in 243 with the 9 twist barrel and slap a 6-24x40mm bushnell elite 4200 on that sucker. Good to go.
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Solving Virginia's Ground Hog problems 50gr at a time.....
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