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I did manage to pick up a can of IMR 4227 though.
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I've never used IMR4227. But it's well understood to be a "magnum" propellant; best suited for full-throttle 357, 41, 44, and larger magnum revolvers. Works best with heavy bullets. I don't believe it is commonly used for anything else. Like most powders of its genre, it likes a heavy roll crimp to get a good, consistent ignition, etc. You know, magnum revolver type stuff.