I would use 158 gr JSP's for whitetail hunting with a 357 mag revolver.
I went through this thinking years ago and reading pretty much everything I could find on handgun hunting. I bought a 6" Colt Python for handgun hunting. I later decided it is not quite powerful enough and went with a 41 mag revolver. I generally recommend JSP's in 41 mag as well for deer hunting. I don't think hard cast bullets are necessary for white tails. Bears are another matter.
The 357 mag is often considered the minimum caliber for deer hunting with a handgun.
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