I've only used Sierras for the last 25 years or so. Looking back, either the 150/165-grain flatbase or the boattails go on through central Texas whitetails of the 120-pound (dressed weight) variety. The 150-grain boattails haven't exited on a couple of mule deer.
Wuz I guessing about what Sierra to use on deer of 150 pounds or more, I'd go with 165- or 180-grains. I'd probably still use the boattails, but I'd not be huffy about it...
I had hellacious exit holes in cenTex deer with the Remington 150-grain Bronze Points, even out at 350 yards.
My father was always partial to the Hornady 150-grain Spire Point, but since he mostly shot his deer in the neck, it's hard to judge about exit wounds for a body shot. (He usually shot offhand. He'd pop the white spot at 200-300 yards, look over with a bit of a smirk...Sumbitch...)
All these bullets grouped within one MOA.
FWIW, Art
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