Along the same lines as g. wilikers, also check you manuals to see what pistol was used to test each load. If, for example, one company used a 4" Glock and another used a 5" 1911 and still a third used a sealed test barrel they will get diffrent data for the same bullet/primer/powder combo. For MOST powders, start at the minimum and work up slowly - not more than 0.2 grains at a time - and watch for pressure signs. You might look at the primers being used, too, since some burn hotter than others and will, therefore, raise pressure faster. Hope this helps.
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