Confined spaces favor the big and slow guy a lot more than they do the small and quick guy. Most small and quick guys need some maneuvering room. Big guys can just use what a large friend of mine used to call the "Amoeba technique" and simply envelop the small person to the floor, after which speed and quick reflexes are much less helpful to the small guy.
Others have already noted the additional potential threat posed by the female who started the whole thing.
If armed, I'd suggest using the weapon in order to have some ability to maintain such distance as there is, and not to get physically tied up with a big dude while losing situational awareness of where the female is.
Females may have knives, guns, or improvised weapons, too.
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