if we assume the density of the two projectiles can be different, it gets interesting. If we must use lead, not so much interesting.
If we take a .22 bullet and hammer it flat to make a .45 "slug" its gonna be like trying to shoot a foil disk and will just crumple and go "pffft"
if we take a .45 slug and make a .22 bullet out of it, it's gonna be a little arrow of lead and good luck getting that launched. Its too noodle like to fly or handle the torque of the rifling.. it will curly-cue or fall apart in the air.
But.. if we can adjust our density... interesting stuff!
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