[E.J.W.]

I shot a deer this season with an old Ruger SA in 45 Colt. First hunt with this revolver. Load was a 250gr RNFP cast at .454" (this 1973 vintage SA has oversize cylinder openings) on top of 16.5gr of 2400. Don't have a chronograph, but it should be near 1000 fps out the 7.5". Very accurate from the bench so once in the field its up to me to perform. He didn't go more than 50 yards. Quick clean kill.
Should make a nice rifle load as well. My next "toy" will be a lever in 45 Colt.
As always reduce any load by 10% and start there.
Good luck.
E.