I don't shoot that many calibers, but for what I do shoot, here's my preferences:
.45 ACP - Titegroup (when I can find it) or Bullseye
.308 - Varget or Vihtavuori 530
.458 Lott - Hodgdon H4895 (but I'm not really thrilled with this powder for this chambering) - may try Reloder 15 one day if I can find it.
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