Remington factory 240's have less energy at 100 than your ammo. Given that you can hit what you're shooting at, I'd say you're all set. Without knowing the math, I suspect your energy figure maybe a bit light. I don't think the bullet would lose 100 ft-lbs in 25 yards. The Remington ammo loses 98 ft-lbs in 50 yards.
Deer vitals aren't as hard nor as dense as 2.5" of wood. You're more likely to see one much closer than 125 though. You may want to sight in at 50 and then shoot at 125 to see where it hits. Mind you, I'm guessing more than you.
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