On a mule deer hunt trip, I took my .375 H&H and my buddy took his 7mm mag. He'll be the first to tell you that his 7mm did WAY more meat damage than my .375 did.
If you want to hunt deer with a .375 H&H, any 270gr soft points should be fine. You can even go down to 235 grain soft points if you want. No matter what bullet you use, a shot through the boiler room will knock him flat.
If an Africa PH will recommend a .375 H&H for everything between a 1500 lb eland to a 15 lb dik dik, I don't see a reason not to use one on whitetail!
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