I can comment on 45-70 heavy, 375 H&H ( Federal "safari" loads with Trophy Bonded Bear Claws ), & 338 Win Mag ( Federal "safari" loads with Trophy Bonded Bear Claws...
my old rifle range backstop used to sit at 200 yards, & was an old chest freezer roughly 2' thick, by 6' wide, which was stuffed as solidly with sheet rock as I could get it...
at 200 yards, both cartridges out of matching Browning stainless stalkers ( 338 had a 2" longer barrel ), both equiped with BOSS systems, were MOA accurate... the major difference was the 338 consistantly went out the back side of the freezer
the 375 never did...
I love both... but they are pretty expensive to shoot...
338...
375...
BTW... 416 is on my "to buy" list... still wrangling if I should do the Remington or the Rigby yet though... can't see myself with a 40 cal... if I were doing another from that group ( though not listed ) it would be the 8mm Magnum...