[BlueTrain]

No, I don't think a relatively slow long large round nose bullets are used when hunting dangerous game, that is, thick skinned animals in particular. You need large fast bullets, though many elephants have been killed with "ordinary" rifle bullets. In any case, you still need to know where to hit the animal. For smaller dangerous animals, you wouldn't need an elephant gun but they could certainly be used. But that kind of stuff doesn't translate much to human targets, though an elephant gun will still work and probably very well.

The problem with bone is that bullets can be deflected, particularly from the skull and believe me, some people are very hard headed. Aside from that, I'd say most service ammunition has enough penetration capability. Very high speed pistol bullets, like .30 Tokarev, will supposedly shatter bones (limbs, that is).