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12 grains of Herco or 16.5 grains of Blue Dot w/ 255 grain cast bullets and any old large pistol primers. Do not shoot these in a SAA or a Ruger New Vaquero (etc), they are Blackhawk and Redhawk and original large-frame Vaquero loads.
You can load hotter using 2400 or AA#9 or 296 (and a few others) but they take a lot more powder for a small increase in performance.
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