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Read the front sections of your load manuals, and not just the actual loading section. The Midway LOADMAP's just give you the minimum information, and nothing else. That front half of the loading books is there for your safety - You ALWAYS start low and work up, and if you change ANYTHING in a max load - a new can of power, a different lot of primers, different make of case, same weight bullet but a diffeent brand with a different shape; back off a little (1 or two steps, that might be 1/2 grain for a small rifle cartridge, a full grain for a magnum, or a tenth of a grain for a small pistol) and work up again.
Different guns will always change the result; even two different pressure barrels will give different velocities/pressures etc. So you start low, and work up to where your gun is gving you good accuracy without any of the pressure signs already mentioned in this thread and your loading manuals; then STOP. An extra 50 fps isn't worth battering your gun or losing accuracy for; and certainly isn't worth blowing up a gun. If you load for more than 1 gun in a caliber, then work up your loads shooting each step in each gun. The results can be surprising with short barrel's sometimes shooting loads faster than a different gun with a longer barrel; a tightly fitted gun may show pressure signs before another gun with a looser chamber or slightly larger bore; etc.
You are responsible for the ammo you load, don't take chances with it unless you are willing to take the consequences of a mistake.
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