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Wyosmith gives good advice. In Alaska the benchmark is the .338 Win. Mag., mostly because of large bears. Tony Russ, renowned sheep hunter, guide, and author used a .338 for sheep hunting because in his words "sheep country is also grizzly country."
For moose and bear, bullet construction, weight and sectional density are more important than velocity. If I were to to carry a .30 cal. for a hunt as you describe, it would be a magnum with 200 grain bonded bullets.
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