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They build firearms intended to fire SAAMI-spec cartridges -- not obscure wildcats or stupidly-overpressure handloads.
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May be generally true, but there is a whole subculture built around their 45 Colt capabilities, well beyond any SAMMI spec. Standard 45 Colt in my 5.5" Redhawk would be really boring, but perhaps a target load, if I was competing with it or shooting bowling pins or some such.