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The 170 and 180 gr bullets seem to perform very reliably both up close and not so close. As you get farther out, the bigger bullets may be subject to limits on effective range due to wind drift concerns.
For longer ranges, the flat shooting pointy plastic tip bullets seem to work pretty good. I have seen a number of reports of good performance at over 200 yards.
In my 357AR, I got 2 moa groups out to 200 yards with a custom cast 200 gr shooting at over 2000 fps. Cast bullets are less likely to give DRT results, but inadequate penetration is certainly not a worry for these loads.
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