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No.
As respectable a cartridge as .45ACP is, it does not knock people off their feet, or automatically throw people through plate glass windows, or kill through near misses or anything else like that. Doesn't matter if you're using FMJ, LRN, JHP, EFMJ, JSP, AP, Glaser, MagSafe, EXTREEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEME SHOCK or cast resin bullets. Just doesn't do it.
It punches nearly half inch holes in stuff, though. That counts for something, right?
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