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Old April 26, 2019, 02:07 PM   #82
Senior Member
Join Date: March 18, 2013
Location: Northeastern US
Posts: 1,787
If you hit something really important, most major defensive calibers will do just fine. If you don't, then differences between calibers could matter. In a messy or entangled defensive encounter in which you might only be able to put one into a thigh, shoulder, hip, gut, etc., then bigger or more energetic could be more helpful.

Look, gel is awesome and tells us a lot. People and animals are not made of gel. We have bone, various tissues, and all sorts of structures. Hydrostatic shock is usually a red herring in terms of handguns. Sometimes, a defensive encounter comes down to destroying or disrupting flesh, bone, mechanically important structures, etc.
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