I have used bullseye, titegroup, unique, and Lovex cleanshot (which they compare to titegroup).
Cleanshot really is a lot cleaner than unique. Of the powders I have experience with, I'm pretty much given to stick with bullseye and cleanshot.
As for primers... 45ACP is the only cartridge I reload that uses LPP, so that is what I prefer. If I run into brass that uses the SPP, I just throw it in a bag for use some other time. SPP's are hard to get, and I have several cartridges I reload that require them. I don't need to throw them at 45 as well.
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