Funny thing is with this ammo shortage we have...
About all I can find on a regular bases IS .44 magnum!
Now as for versatility, I think any of the big Berthas are pretty versatile.
Nothing bad about a .45 LC or .41 Magnum. Even the .454 and .460 can be loaded down.
But keep in mind the platform. A huge pistol is not so versatile and thus there is a limit on the whole combination of gun and cartridge.
I'm real happy with my 626-2 4 inch .44 magnum.
And it is plenty for me. I can pack it easily and load it up or down as needed.
But a good .45 LC in the same package would do well to, as would a .41 Magnum.
Deaf