Get her a 3” GP100 or 4” S&W 13…..or maybe a J-frame size like a model 60 3”.
Then load it with snake shot for round 1….the remaining rounds would be 38 special or 38 +p.
To me, the key would be getting her a holster she can live with. The holster is key because it can support the weight better than pocket carry. A chest holster would be ideal or maybe a 4 o’clock position.
S&W 13 3” Handguns Mag Article