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To amplify Zak's comments, the 260 has a perfect expansion ratio - the bore to capacity. Most of the AI calibers on the 2 inch(308) case don't gain any marked improvement. If you shoot standard stuff in an AI, you'll have some accuracy/velocity challenges.
PS. Just thought of one other thing you might consider. When I had my .338-06 built, I had it throated for 250 Partitions. For most hunting, I use 200 Hornady or Speer. In a 22" barrel, I'm getting 2810 over the chrony. I had the same thing done with my 6.5-06, throated for 140 SierraBT. The 6.5 gives 3200 with 120s, 3100 with 125s, and 2935 with 140 Hornady - in a 24" barrel. That is 264Win territory.
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