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Can't go wrong with any of the three - .270, .30-06, or 300 Win Mag.
I have a .308 and .300 Win Mag (as well as a .44 Ruger Carbine) and I'd hunt with either for anything up to Elk/Moose.
.270 and .30-06 will be easy to find and there are a world of loads out there for them. The .300 Win Mag is overkill on deer to many people, but I use 150 grain loads for deer when using the 300.
Lots of good choices, just boils down to your needs (distance, skill, reloading capability, etc.).
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