As predicted, a universally bad idea, but the reasons why were interesting.
I have heard of a lot of different combination loads for HD shotguns. Birdshot first (to make sure you hit someone) followed by combinations of 00, slugs, to all sorts of "exotic" loads like flechettes and bean bags and fireballs. Some of those ideas may have merit, but for the revolver seems like no mixing = best plan.
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