The answer is simple "You do whatever keeps you alive". Doing what it takes to stay alive is the hard part, and there is no clear cut answer, but you have to be ready to react when you need to and you have to react quickly and correctly at the moment of truth.
That means practice in doing anything and everything that might be required of you to do to stay alive in a fight. It's a skill set, not a choice as to which is the best do all be all.
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