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My pick is for the 243. Yes the 6.5 uses a heavier bullet slightly larger in diameter. But bigger doesn't mean it kills faster or better. Shot placement is what is important here. Also, ammunition for a 243 is available almost anywhere and everywhere. A lot of deer have fallen to our 243, all one shot kills. Both are great calibers and will kill deer. And if you reload, cases are readily available, and cheap. You can find them at shooting ranges, sometimes not always, for free. So my vote is for the good old 243.
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